Area of Effect

Area of Effect refers to Spells and Abilities that can affect multiple targets within a specified area. Area of Effect Skills also known as AoE Skills are often most effective when used on groups of enemies. These type of Skills are also often used for Crowd Control.

Some examples of Damaging AoE Spells include Frost Nova, Blizzard and Meteor. Other AoE examples include Grasp of the Dead and Sacrifice.

Splash Damage is similar to Area of Effect, except for the fact that Splash Damage typically deals more damage to the target at the center of the impact than it does to targets on the edge of the Splash Damage radius. Area of Effect damage is usually distributed equally to all targets caught in the area of effect.

Also See:
Multiple Targets
Chain Effects

The Following Is A List Of Each Class' Skills That Do Area of Effect Damage or Abilities that Have An Effect On All Enemies In A Particular Area.
 

Barbarian Skills That Affect Multiple Targets In An Area

Battle Rage (Bloodshed)
Cleave
Cleave (Rupture)
Ground Stomp (Avalanche)
Leap Attack
Weapon Throw (Dread Shot)
Weapon Throw (Ricochet)
Ground Stomp
Hammer of the Ancients
Rend
Frenzy (Sidearm)
Furious Charge
Overpower
Seismic Slam
Seismic Slam (Rumble)
Whirlwind
Whirlwind (Dust Devils)
Wrath of the Berserker (Slaughter)

Demon Hunter Skills That Affect Multiple Targets In An Area
Hungering Arrow (Spray of Teeth)
Impale (Awareness)
Caltrops
Evasive Fire (Parting Gift)
Evasive Fire (Shrapnel)
Bola Shot
Vault (Rattling Roll)
Grenades
Fan of Knives
Spike Trap
Spike Trap (Sticky Trap)
Multishot
Rapid Fire (Bombardment)
Smoke Screen (Choking Gas)
Strafe (Demolition)
Marked for Death (Grim Reaper)
Marked for Death (Valley of Death)
Cluster Arrow 

Monk Skills That Affect Multiple Targets In An Area

Fists of Thunder (Thunderclap)
Blinding Flash
Blinding Flash (Blinding Echo)
Inner Sanctuary
Lashing Tail Kick (Hand of Ytar)
Cyclone Strike
Serenity (Reap What is Sown)
Mantra of Retribution (Collateral Damage)

Witch Doctor Skills That Affect Multiple Targets In An Area

Plague of Toads (Rain of Toads)
Grasp of the Dead
Zombie Charger (Explosive Beast)
Zombie Charger (Zombie Bears)
Hex (Angry Chicken)
Hex (Unstable Form)
Corpse Spiders (Spider Queen)
Firebats (Plague Bats)
Firebomb
Spirit Walk (Umbral Shock)
Sacrifice
Spirit Barrage (Phantasm)
Acid Cloud
Acid Cloud (Kiss of Death)
Acid Cloud (Corpse Bomb)
Big Bad Voodoo

Wizard Skills That Affect Multiple Targets In An Area

Arcane Orb
Shock Pulse (Explosive Bolts)
Spectral Blade (Thrown Blade)
Disintegrate (Volatility)
Energy Twister
Electrocute (Arc Lightning)
Mirror Image (Mocking Demise)
Explosive Blast
Hydra (Arcane Hydra)
Hydra (Frost Hydra)
Hydra (Brimstone Serpent)
Hydra (Venom Hydra)
Ray of Frost (Black Ice)
Ray of Frost (Sleet Storm)
Arcane Torrent (Arcane Mines)
Familiar (Cannoneer)
Blizzard
Blizzard (Grasping Chill)
Meteor
Archon (Arcane Destruction)

Follower Skills That Affect Multiple Targets In An Area
Scoundrel (Powered Shot)
Enchantress (Forceful Push)
Enchantress (Disorient)
Enchantress (Scorched Earth)