Multiple Targets

In Diablo 3 there are many Skills and Abilities can affect Multiple Targets at once. The number of targets affected depends on the Skill or Ability used.

Also See:
Area of Effect
Chain Effects

The Following Is A List Of Each Class' Skills That Can Affect Multiple Targets:

Barbarian Skills That Affect Multiple Targets

Cleave
Ancient Spear (Harpoon)

Demon Hunter Skills That Affect Multiple Targets

Evasive Fire (Covering Fire)
Entangling Shot (Chain Gang)
Fan of Knives (Assassin's Knives)
Companion (Boar Companion)

Monk Skills That Affect Multiple Targets

Deadly Reach (Scattered Blows)
Exploding Palm (Creeping Demise)
Seven-Sided Strike

Witch Doctor Skills That Affect Multiple Targets

Firebomb (Flash Fire)
Locust Swarm (Pestilence)
Gargantuan (Humongoid)
Spirit Barrage (Well of Souls)

Wizard Skills That Affect Multiple Targets

Magic Missile (Split)
Magic Missile (Penetrating Blast)
Electrocute
Electrocute (Forked Lightning)
Arcane Torrent
Meteor (Meteor Shower)

Follower Skills That Affect Multiple Targets

Scoundrel (Multishot)